Welcome: Avenir Biotech (Hong Kong) Limited

Untargeted Metabolomics

Service description:
Metabolites are extracted before proceeding with Orbitrap Exploris 480 for mass spectrometry analysis. After that raw spectrum will be aligned with public database for metabolites identification . Bioinformatic tools will also be used for differential metabolites analysis.

Sample requirement:
Tissue amount ≥ 40mg
Cell number ≥ 1M

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Untargeted metabolomics is a comprehensive, unbiased approach to measuring as many small-molecule metabolites as possible in a biological sample to discover novel pathways and generate new hypotheses.


Major Applications:

  • Biomarker Discovery: Identifies unique molecular signatures or differential metabolites tied to specific health conditions, diseases, or environmental exposures

  • Disease Diagnosis and Pathophysiology: Uncovers underlying disease mechanisms and metabolic shifts for conditions such as cardiovascular disorders, cancers, and inherited metabolic disorders.

  • Microbiome Research: Characterizes the metabolic crosstalk and systemic biochemical interplay between a host organism and its gut microbiota.

  • Drug Discovery and Personalized Medicine: Evaluates unexpected metabolic changes and efficacy resulting from therapeutic interventions or genetic variations.

  • Environmental Biomonitoring: Detects and tracks human or ecological exposure to a broad spectrum of environmental contaminants and toxins.

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